4.2 CropScience

Research fields and sites

CropScience maintains a global network of research and development facilities. Our largest R&D sites are as follows:

Research and Development Sites

Site
Country
Focus

Monheim

Germany

R&D of crop protection products, focus on insecticides

Frankfurt

Germany

R&D of crop protection products, focus on herbicides

Lyon

France

R&D of crop protection products

Sophia Antipolis

France

R&D of crop protection products

Raleigh / Research Triangle Park

U.S.A.

R&D of crop protection products; research center for seeds, focus on cotton

Sacramento

U.S.A.

R&D of crop protection products

Ghent

Belgium

Research center for seeds

Nunhem

Netherlands

Research center for vegetable seeds

Lubbock

U.S.A.

Research center for seeds, focus on cotton

Morrisville

U.S.A.

Research center for seeds

While research is carried out centrally at a small number of sites, our development and plant breeding activities take place both at these sites and at numerous field testing stations across the globe. This ensures that future active ingredients and crop varieties can be tested according to specific regional and local requirements. The research centers of the Seeds unit focus on improving seed and targeted seed traits through seed technology and breeding.

In November 2015, CropScience opened three new institutes within the research and innovation center at Paulínia, Brazil: the company’s first applications technology center outside of Germany, a resistance monitoring laboratory and a center for agriculture in tropical regions.

Crop Protection / Seeds

Research fields

In Crop Protection / Seeds our scientists working across the fields of improved seed traits, seed technology, seed breeding, agricultural chemistry and biologics closely collaborate as part of our integrated research approach. This optimally bundles the technical expertise acquired in chemical and biological research and field development, aligning it with our long-term research objectives and business strategies for the various crops.

In the Crop Protection unit, we pursue the goal of identifying and developing innovative, safe products for use as insecticides, fungicides, herbicides or seed treatments in sustainable agriculture. In the fields of chemistry, biology and biochemistry, modern technologies such as high-throughput screening and bioinformatics play an important role in identifying new chemical lead structures. In addition, we are broadening the range of uses for our active ingredients by developing new mixtures or innovative formulations to enable their application in additional crops or in different regions and make them easier to handle. Successful collaborations with external partners complement our own activities.

Research in our Seeds unit is devoted to optimizing plant traits. We are developing new varieties in our existing core crops – cotton, oilseed rape / canola, rice and vegetables. We have now expanded our research activities to include two further core crops – wheat and soybeans. Our work focuses on improving the agronomic traits of these crops. Our researchers are working to increase the quality and yield potential of crop plants – for example by improving the profile of rapeseed oil or enhancing the properties of cotton fibers. We are also targeting the development of plants that have high tolerance to external stress factors such as drought, and can more efficiently utilize water. Further areas of focus include developing new herbicide tolerance technologies based on alternative modes of action, and improving insect resistance and disease tolerance. To do this we employ modern breeding techniques ranging from marker-assisted breeding to plant biotechnology methods.

Technological advances offer farmers faster and more accurate methods of monitoring their plants. Such digital solutions can help them to better understand processes in their fields and enable them to make quicker and simpler decisions and calculate the risks more effectively. We would like to support this development in the future by giving farmers specific agronomic recommendations. Therefore, in addition to our conventional research projects, we are developing digital products in which we augment field analyses and statistical models with additional data that we can adapt or individualize for a certain field in order to help our customers to make decisions.

New products and registrations

In 2015, CropScience once again attained a series of important new registrations. In January 2015, for example, we received regulatory approval from the u.s. Environmental Protection Agency (EPA) for the new insecticide Sivanto™ , which controls sucking pests on fruits and vegetables as well as most broad-acre crops. Based on the active ingredient flupyradifurone, Sivanto™ is a novel systemic insecticide. CropScience received marketing authorization for this product in Mexico and South Korea in the spring of 2015, and flupyradifurone was approved by the European Commission in November 2015. We anticipate attaining the first national registrations for Sivanto prime™ in European countries in 2016; its market launch is planned for 2017.

The product Council™ was already granted regulatory approval in South Korea in 2014 and it has been available there since the 2015 planting season. The new rice herbicide will considerably improve weed control, as it features a favorable environmental profile and outstanding compatibility – characteristics that make Council™ an environmentally friendly and future-oriented product in the Asian rice market.

In August 2015, CropScience received marketing authorization from the European Commission for terpenoid blend QRD 460, the active ingredient in the product Requiem. This biological insecticide serves to control sucking pests. Its market launch in Europe is scheduled for 2017.

In September 2015, CropScience opened a new building for its European Wheat Breeding Center in Gatersleben, Germany. Our wheat activities focus primarily on the development of hybrid seed that promises considerably improved yield stability compared with conventional seed and is scheduled for launch after 2020. CropScience announced in September 2014 that it will invest a total of €1.5 billion in the research and development of wheat seed and crop protection between 2010 and 2020. Here CropScience combines the discovery and development of plant traits, molecular breeding and the latest IT applications in order to optimize the genetic potential of wheat seed in terms of increased yields. In 2015, we took the first step in this direction by launching our first conventional wheat seed in Ukraine.

With many crops, such as vegetables, major success can be achieved using conventional plant breeding methods. As vegetables are intended especially to be marketed and eaten fresh, merchants and consumers have particularly strict requirements regarding their appearance, nutrient content, taste and shelf life. We are launching a succession of new vegetable seed varieties that satisfy these requirements.

Acquisitions and cooperation

In February 2015, representatives of Bayer CropScience and GLOBALG.A.P is a globally recognized quality assurance system in the agriculture industry that is focused on food safety and good agricultural practice. It employs modular and customer-specific solutions for the certification and inspection of agricultural enterprises and the establishment of training programs. GLOBALG.A.P standards focus on product safety, environmental compatibility and the health, safety and well-being of people and animals. . signed an agreement to further intensify their collaboration. The partners aim to implement sustainable cultivation methods and help fruit and vegetable growers worldwide to meet GLOBALG.A.P. certification standards.

Around the world, weed resistances to herbicides jeopardize agricultural efficiency and sustainability. CropScience has significantly expanded its herbicides research capacities in order to be able to more rapidly offer new solutions to global agricultural problems: in June 2015, CropScience and the Grains Research & Development Corporation (GRDC) entered into a five-year innovation partnership centered partly on the accelerated discovery and development of new active ingredients to manage major and resistant weed species. The GRDC will finance the expansion of existing capacities at the global herbicides research center of CropScience in Frankfurt to include some 40 additional scientists and technicians.

In June 2015, CropScience announced the acquisition of SeedWorks India Pvt. Ltd., headquartered in Hyderabad, India. The company is specialized in the breeding, production and marketing of hybrid seeds of tomato, hot pepper, okra and gourds. Existing and forthcoming varieties will be marketed under CropScience’s Nunhems™ brand.

In September 2015, CropScience and the Round Table on Responsible Soy (RTRS) announced that they would jointly assist soybean producers in the certification of their crops according to RTRS standards. RTRS certification guarantees that soybeans – whether used as a raw material or in processed products – originate from environmentally friendly, socially compatible and economically viable production. This collaboration will initially be focused on Brazil.

Special mention should be made of our food chain partnerships, in which CropScience supports all the players in the food chain – from farmers and food processors to importers, exporters, wholesalers and retailers. CropScience has participated worldwide in food chain partnership projects for 10 years, particularly in Asia, Latin America and Europe. Some 7,400 Bayer experts advise farmers on sustainable cultivation methods – from seed selection and the controlled, eco-friendly use of crop protection products to the transparent monitoring of production and assistance in attaining certifications.

Online annex: 3-4.2-1:

limited assurance

Our cooperation with partner organizations in these joint projects is now an internationally successful business model for all participants in the food chain. Smallholder farmers in developing countries and Emerging Markets draw particular benefit from the improved production and marketing structures. Since 2014, we have significantly expanded our partnership with Unilever. This includes a food chain partnership project in Kenya focused on rapeseed whose integrated solution comprises crop protection, seed and support in certification attainment and agronomic training measures. The goal of the project is to stabilize or even increase harvest yields and quality, and thus farmers’ incomes.

CropScience is part of a global network of research and industry partners from diverse segments of the agriculture industry, chemical and biological research, and the food industry. An overview of the major research partnerships is contained in online annex: 3-4.2-2

Online annex: 3-4.2-2:

limited assurance

CropScience: Important R&D Collaborations

Cooperation objective

Increase in wheat yields by means of native plant traits – discovery, validation and integration

Use of microbes to improve soil health and thereby increase crop productivity

Herbicide Innovation Partnership for the discovery and development of innovative weed management solutions

Joint development of new substances to control mosquitoes that transmit diseases such as malaria and dengue fever

Development and application of systems biology approaches to achieve a better understanding of metabolic processes in plants

Integrated research and development pipeline

Group target 2015:

transfer of two new molecular entities (NMEs) or plant traits into confirmatory technical proof-of-concept field studies

Our integrated product pipeline for crop protection and seed technology contains numerous new crop protection products, seed varieties and enhanced products (life cycle management) that have estimated launch dates between 2014 and 2019. We believe these products have a combined peak sales potential in excess of €5 billion. In line with our Group target 2015 we launched confirmatory technical proof-of-concept field studies for one new molecular entity, one new plant trait and two new biologics. A new plant trait is a specific characteristic that has not yet been available or offered at Bayer for the crop plant in question.

The table lists a selection of products launched in 2015 and market launches expected through 2019:

Innovation Pipeline1

Indication / crop
Product / plant trait
Product group
Market launch2

Insecticide

Sivanto™

Chemical crop protection

2015

Herbicide

Council™

Chemical crop protection

2015

Wheat

Conventional seed

Seeds

2015

Oilseed rape / canola

Dual herbicide tolerance

Seeds

2016

Insecticide

New active ingredient

Biological crop protection

2017

Cotton

Dual herbicide tolerance and insect resistance

Seeds

2017

Oilseed rape / canola

Dual herbicide tolerance

Seeds

2017

Oilseed rape / canola

Herbicide tolerance

Seeds

2017

Soybeans

Dual herbicide tolerance

Seeds

2017

Insecticide

New active ingredient

Chemical crop protection

2019

Fungicide

New active ingredient

Chemical crop protection

2019

Soybeans

Triple herbicide tolerance

Seeds

2019

Soybeans

Dual herbicide tolerance

Seeds

2019

1 Selected new products
2 2016-2019: planned market launch
As of January 6, 2016

Environmental Science

Research fields

Environmental Science offers consumers and professional users chemically and biologically based pest and weed control solutions by tailoring substances from our Crop Protection unit or external partners for use in the garden, on golf courses, on road- or railways or in forestry.

Activities in 2015

Environmental Science expanded its product range for professional users in the Middle East by introducing various innovative formulations of our insecticide Maxforce™. The new biological product Dedevap Green™ is available in Germany for use in granaries. Environmental Science also cooperates with companies in Brazil and Argentina to promote sustainable forestry – through the use of products such as our herbicide Esplanade Forest™, which enables reduced application of herbicides thanks to its long-lasting effect. We are continuously expanding our range of fungicides. Examples here include the launch of Dedicate™ in Europe, Chipco Signature Xtra™ in the United States and the biological nematicide Nortica™.

For consumers we continued to work in 2015 on the development of innovative and user-friendly packaging and the expansion of our range of biological solutions. We rounded out our range of pest and weed control products with the launch of the new fungicides Consento™ and Emerald™ in central Europe and Italy, the snail control product Dismo™ in France and Austria and new formulations of Decis Garten™ in Italy and the Benelux countries.

For more than 50 years, Bayer has played an active role in the fight against malaria, which remains one of the most dangerous tropical diseases to this day. Environmental Science is a leading supplier of indoor spray insecticides that control malaria-transmitting mosquitoes, protecting some 50 million people a year from the disease. In 2015, Environmental Science received support from the World Health Organization of the United Nations (WHO) for the use of the Fludora™ brand to combat malaria within the context of integrated pest management. Environmental Science is also currently developing a new outdoor spray, K-Othrine Polyzone™, to combat dengue fever in Southeast Asia. This product is targeted for launch in 2017.